Dietary Patterns in Alzheimers Disease and Cognitive Aging

Dietary patterns in Alzheimer's disease and cognitive aging.

Much of the attention on diet and Alzheimer's disease (AD) or cognition among the elderly has focused on the role of single nutrients or foods, while available information on dietary pattern (DP) analysis, which better reflects the complexity of the diet, is sparse. In this review, we describe different patterning approaches and present studies performed to date that have assessed the associati...

Molecular and Cellular Mechanisms of Neuronal Plasticity in Normal Aging and Alzheimers Disease

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Cognitive aging and Alzheimer's disease.

Cognitive aging and clinically probable Alzheimer's disease can be discriminated by means of clinical and neuropsychological testing, and structural and functional imaging techniques. Research at the level of cognitive brain systems and at the molecular level provides exciting new insights into the relation between aging and neurodegeneration. The advances at the clinical and at the basic resea...

Specific Agonists and Antagonists of Serotonergic Receptors in the Treatment of Cognitive Symptoms in Alzheimers Disease

In Alzheimer’s disease, decreasing activity of acetylcholine and GABA in the hippocampus and prefrontal cortex are combined with cognitive deficits and with the formation of beta-amyloid. Neurotransmitter alterations in these brain regions are described, while a neurotransmitter imbalance with hypoactivity of muscarinic cholinergic, serotonergic and GABAergic neurons and hyperactivity of noradr...

Cognitive Impairments in Siblings of Alzheimers Disease Patients: Possible Preclinical Signs of the Disease